A Test That Could Predict Alzheimer’s

The best health advice is to prevent health problems from occurring. The best method of prevention is understanding and avoiding risks, and detecting issues as early as possible. On that note, we present a health breakthrough in area of dementia, namely Alzheimer’s disease. Researchers have found that, using a simple MRI test, we could help predict which adults are more likely to develop Alzheimer’s.

Let’s begin with “mild cognitive impairment,” as it is central to this latest health news. This is the intermediate stage between the natural decline in mental abilities that happens when we age and the more pronounced decline that occurs with Alzheimer’s. The study suggests that MRI scans could help predict which people with mild cognitive impairment (MCI) are most at risk of progressing to Alzheimer’s.

People with MCI develop Alzheimer’s at a rate of 15% to 20% a year. This is far higher than the rate of the general population, which sits at about one to two percent. Some people with MCI remain stable, some have gradual decline, and some have rapid deterioration. Predicting who does what would be an immeasurable benefit for patients.

The team analyzed MRI exams from a study on 203 healthy individuals, 317 with MCI and 164 with late-onset Alzheimer’s, between 2005 and 2010. They conducted a MRI exam at the beginning, then another one year later. The patients’ average age was 75. The MRI measured thickness of the cerebral cortex; the outer layer of the parts of the brain in charge of memory, attention, thought and language. The question was how quickly this area started to thin out. One hallmark of Alzheimer’s is a loss of brain cells in areas of the cortex.

They found that patients with MCI had a one-year risk of conversion to Alzheimer’s ranging from three percent to 40%. The MRI at the beginning helped identify those patients at very low risk of Alzheimer’s and those whose risk was doubled. Combining both MRI exams could predict rates of disease progression between three percent and 69%.

Sadly, no current treatments truly slow or prevent Alzheimer’s. But this information can help considerably with quality of life, family planning, and many other factors for patients. Speak to your doctor for more information.

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About the author

author-picture

Dr. Victor Marchione received his Bachelor of Science Degree in 1973 and his Medical Degree from the University of Messina in 1981. He has been licensed and practicing medicine in New York and New Jersey for over 20 years.

Dr. Marchione is a respected leader in the field of smoking cessation and pulmonary medicine. He has been featured on ABC News and World Report, CBS Evening News with Dan Rather and the NBC Today Show and is the editor of the popular The Food Doctor newsletter.

Dr. Marchione has also served as Principal Investigator in at least a dozen clinical research projects relating to serious ailments such as bronchitis, pneumonia, asthma, and chronic obstructive pulmonary disease (COPD).


Comments

Anonymous's picture
1

Anonymous

No point in commenting, if I can't read the comments of others...who's gonna read this...anyone? I seriously doubt it will be made public!! I'm Gone!

Anonymous's picture
2

Lori

"Sadly, no current teatments truly slow or prevent Alzheimer's." That's because we're looking in the wrong place. With all due respect to Dr. Marchione, an MRI is not true prevention. By then, it may too late. There's research that shows that vitamin D deficiency may be related to cognitive decline.
http://www.webmd.com/healthy-agi...
The same goes for omega-3 fatty acids.
http://newsletter.vitalchoice.co...
http://www.ncbi.nlm.nih.gov/pubm...
http://www.ncbi.nlm.nih.gov/pubm...
It's the fact that we're starving for nutrients that we develop chronic disease.

Anonymous's picture
3

Anonymous

Thank you, Dr. Marchione for the most sensible article I have
read yet.....and I have read hundreds in the past 5 years. It
would mean peace of mind for patients and their families to
have the MRI test and know what to expect and how to plan
for the changes expected.

Take it from someone who has been there and done that!
You can not even imagine the emotional stress and strain one
goes through when you have a patient on the edge of dementia and don't have a good clue as to what is happening!
Get that MRI if you think it is needed even if you have to fight
the doctor and health insurance company to get their consent.

Anonymous's picture
4

Anonymous

With all due respect, anyone suggesting an MRI for something already known that due to the fact that cognitive declined patients have excess amounts of aluminum in the brain, now this tells me that we should avoid the intake of fluoride as much as possible instead of subjecting suspected patients with all these radiations, there has to be a logic somewhere instead of all these harmful treatments, and yes I agree that nutrients plays a major role in our health. JAM

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