Vitamin E "rescues" brain after stroke
Previously I've talked about vitamin E and bladder cancer. But, really, we've just scratched the surface. There‘s so much more to learn about this powerful antioxidant. According to a new study, vitamin E may protect you against brain damage following a stroke. Scientists say they‘ve never seen anything like it. Even small amounts of the vitamin appear to protect precious brain cells following a stroke.
Too much of a good thing...
A stroke occurs when a blood vessel leading to your brain gets blocked or ruptures. Your body wants to repair the damage. But it overreacts and causes more harm than good.
In fact, following a stroke, your brain releases a neurotransmitter called glutamate. In normal amounts, glutamate helps with learning and memory. But too much glutamate sets off a chain reaction that kills brain cells. And this sudden loss of brain cells is what‘s to blame for most of the long-term damage from a stroke.
This is also why time is of the essence when responding to a stroke. The faster you remove the blockage, the less glutamate flooding into the brain, the fewer brain cells killed.
But scientists from the Ohio State University (OSU) have recently found another way to block the damage caused by excess glutamate in stroke victims‘ brains.
You got it: vitamin E.
Not just any vitamin E will do...
As you‘ll recall, vitamin E is a collection of eight different molecules. We don‘t know a lot about the roles each of these molecules play in human health. And we probably know the least about the one fraction of vitamin E called alpha- tocotrienol. And that‘s exactly the fraction that OSU scientists used in their recent stroke experiments...
First, OSU scientists divided lab mice into two groups. The first group of mice got no vitamin supplementation. The second group of mice received a daily regimen of alpha-tocotrienol. (But they didn‘t get a lot. In humans, it would be like cutting your vitamin E supplement into 10 pieces. If you took just 1 piece of it each day, you‘d get the equivalent of what the second group of mice received.)
Next, the scientists injected all the mice with glutamate (to simulate what occurs in the brain following a stroke). In the non-vitamin group, the glutamate triggered the release of a toxic enzyme called cPLA2. This toxic enzyme poisoned the animals‘ brain cells, causing massive brain cell death.
But how did the mice given alpha-tocotrienol do?
Saving brain cells...without a drug in sight
The glutamate injection still triggered the release of cPLA2 in the second group of mice. But it caused much less damage. In fact, the mice who took alpha- tocotrienol reduced their glutamate and cPLA2 levels by 60 percent following the stroke. As a result, these mice saved four times as many brain cells than the group without alpha-tocotrienol.
Just think about that...four times as many brain cells saved! In humans, would that make all the difference in saving your ability to speak? Or being able to feed yourself?
Here‘s how the study‘s lead researcher summed up their results: "Our research suggests that the different forms of natural vitamin E have distinct functions. The relatively poorly studied tocotrienol form of natural vitamin E targets specific pathways to protect against neural cell death and rescues the brain after stroke injury...So what we have here is a naturally-derived nutrient, rather than a drug, that provides this beneficial impact."
Imagine that! A mainstream scientist going on record that a vitamin, not a drug, can protect you against brain damage following a stroke.
And believe it or not the National Institutes of Health funded the study! Maybe we are starting to make small inroads into mainstream medicine, after all? Now, if only we could get rid of all that garbage on TV during football season telling you to take a drug to lower your risk of stroke!
Keeping it natural
Sure, we‘ve still got a long way to go before proving vitamin E does the exact same thing in humans. But believe it or not, mice and human have a lot in common. Our brains react in the exact same way when exposed to glutamate. Plus, OSU scientists believe that vitamin E will protect human brains in the same way it helped the mice.
It‘s pretty tough to get enough vitamin E from your food sources. You‘d have to eat a lot of almonds and wheat germ oil to get what you‘ll find in just one vitamin E supplement.
I recommend finding a high-quality gel cap that contains all eight molecules. On the label, look for a blend of "mixed" tocopherols and tocotrienols. (They should be listed on the bottle as: alpha, beta, delta, and gamma tocopherol; and alpha, beta, delta, and gamma tocotrienol.)
You‘ll also want to make sure only to take the natural forms of vitamin E, not synthetic.
About the author
Nationally acclaimed as America’s “Nutrition Physician,” Dr. Spreen has been helping people stay healthy and disease-free as a private doctor, published author, and noted researcher.
In addition to his role as a Senior Member of the prestigious Health Sciences Institute Advisory Panel in Baltimore, MD, Dr. Spreen also coaches diving at the international and Olympic levels. NorthStar Nutritionals is proud to have Dr. Spreen as our Chief Research Advisor.
Dr. Spreen also writes the Guide to Good Health.